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Alsaid, B., Bessede, T., Karam, I., Abd-Alsamad, I., Uhl, J.-F., Benoît, G., Droupy, S. & Delmas, V. Coexistence of adrenergic and cholinergic nerves in the inferior hypogastric plexus: anatomical and immunohistochemical study with 3D reconstruction in human male fetus. 2009 J Anat
Vol. 214(5), pp. 645-654 
article DOI URL 
Abstract: Classic anatomical methods have failed to determine the precise location, origin and nature of nerve fibres in the inferior hypogastric plexus (IHP). The purpose of this study was to identify the location and nature (adrenergic and/or cholinergic) of IHP nerve fibres and to provide a three-dimensional (3D) representation of pelvic nerves and their relationship to other anatomical structures. Serial transverse sections of the pelvic portion of two human male fetuses (16 and 17 weeks' gestation) were studied histologically and immunohistochemically, digitized and reconstructed three-dimensionally. 3D reconstruction allowed a 'computer-assisted dissection', identifying the precise location and distribution of the pelvic nerve elements. Proximal (supra-levator) and distal (infra-levator) communications between the pudendal nerve and IHP were observed. By determining the nature of the nerve fibres using immunostaining, we were able to demonstrate that the hypogastric nerves and pelvic splanchnic nerves, which are classically considered purely sympathetic and parasympathetic, respectively, contain both adrenergic and cholinergic nerve fibres. The pelvic autonomic nervous system is more complex than previously thought, as adrenergic and cholinergic fibres were found to co-exist in both 'sympathetic' and 'parasympathetic' nerves. This study is the first step to a 3D cartography of neurotransmitter distribution which could help in the selection of molecules to be used in the treatment of incontinence, erectile dysfunction and ejaculatory disorders.
BibTeX:
@article{Alsaid2009,
  author = {Bayan Alsaid and Thomas Bessede and Ibrahim Karam and Issam Abd-Alsamad and Jean-Francois Uhl and Gérard Benoît and Stéphane Droupy and Vincent Delmas},
  title = {Coexistence of adrenergic and cholinergic nerves in the inferior hypogastric plexus: anatomical and immunohistochemical study with 3D reconstruction in human male fetus.},
  journal = {J Anat},
  year = {2009},
  volume = {214},
  number = {5},
  pages = {645--654},
  url = {http://dx.doi.org/10.1111/j.1469-7580.2009.01071.x},
  doi = {http://dx.doi.org/10.1111/j.1469-7580.2009.01071.x}
}
Alsaid, B., Karam, I., Bessede, T., Abdlsamad, I., Uhl, J.-F., Delmas, V., Benoît, G. & Droupy, S. Tridimensional computer-assisted anatomic dissection of posterolateral prostatic neurovascular bundles. 2010 Eur Urol
Vol. 58(2), pp. 281-287 
article DOI URL 
Abstract: BACKGROUND: Detailed knowledge of nerve distribution in the neurovascular bundle (NVB) is essential to preserve sexual function after prostatic surgery. OBJECTIVE: To identify the location as well as the type (adrenergic, cholinergic, and sensory) of nerve fibres within the NVB and to provide a three-dimensional (3D) representation of their structural relationship in the human male foetus. DESIGN, SETTING, AND PARTICIPANTS: Serial transverse sections were performed every 150-200 microm in the pelvic portion of six human male foetuses (15-20 wk of gestation). Sections were treated with histologic and immunohistochemical methods (hematin-eosin-safran, Luxol Fast Blue, immunolabelling of protein S100, vesicular acetylcholine transporter, tyrosine hydroxylase, calcitonin gene-related peptide, and substance P). The 3D pelvic reconstruction was obtained from digitised serial sections using WinSurf software. MEASUREMENTS: NVB nerve location and type were evaluated qualitatively. RESULTS AND LIMITATIONS: The 3D reconstruction allowed precise identification of pelvic organ innervation. Nerve fibres derived from the inferior hypogastric plexus followed two courses: posterior and lateral, providing cholinergic, adrenergic, and sensory innervation to seminal vesicles, vas deferens, prostate, and urethral sphincter. Cavernous nerve fibres did not strictly follow the NVB course; they were distributed at several levels, in a fanlike formation. The main limitations of this study were the limited number of specimens available due to legal restriction and the time-consuming nature of the manually performed stages in the method. CONCLUSIONS: The distribution of nerve fibres within the posterolateral prostatic NVB and the existence of mixed innervation in the posterior and lateral fibre courses at the level of the prostate and seminal vesicles give us an insight into how to minimise effects on sexual function during prostatic surgery. The 3D computer-assisted anatomic dissection represents an original method of applying anatomic knowledge to surgical technique to improve nerve preservation and decrease postoperative sexual complications.
BibTeX:
@article{Alsaid2010,
  author = {Bayan Alsaid and Ibrahim Karam and Thomas Bessede and Issam Abdlsamad and Jean-François Uhl and Vincent Delmas and Gérard Benoît and Stéphane Droupy},
  title = {Tridimensional computer-assisted anatomic dissection of posterolateral prostatic neurovascular bundles.},
  journal = {Eur Urol},
  year = {2010},
  volume = {58},
  number = {2},
  pages = {281--287},
  note = {ordureau},
  url = {http://dx.doi.org/10.1016/j.eururo.2010.04.002},
  doi = {http://dx.doi.org/10.1016/j.eururo.2010.04.002}
}
Ami, O., Chabrot, P., Uhl, J.-F., Boyer, L., Mage, G. & Delmas, V. Reconstruction 3D du canal de naissance et simulation d'accouchement 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Ami2010,
  author = {Olivier Ami and Pascal Chabrot and Jean-Francois Uhl and Louis Boyer and Gérard Mage and Vincent Delmas},
  title = {Reconstruction 3D du canal de naissance et simulation d'accouchement},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Ami, O., Mabille, M., Ordureau, S., Rivka, D.B., Meyo, M.T., Mejean, E., Rousset, L., Uhl, J.-F., Frydman, R., Delmas, V. & Musset, D. Explorateur anatomique du squelette foetal en 3D pour l'étude de l'anatomie normale et pathologique 2010 92ème Congrès de l'Association des Morphologistes, Bordeaux  conference DOI  
BibTeX:
@conference{Ami2010a,
  author = {Olivier Ami and Mylene Mabille and Sylvain Ordureau and Desimeur Bendridhem Rivka and Manuela Tiako Meyo and Elodie Mejean and Laurie Rousset and Jean-Francois Uhl and Rene Frydman and Vincent Delmas and Dominique Musset},
  title = {Explorateur anatomique du squelette foetal en 3D pour l'étude de l'anatomie normale et pathologique},
  booktitle = {92ème Congrès de l'Association des Morphologistes, Bordeaux},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Ami, O., Ordureau, S., Uhl, J.-F., Garcier, J., Boyer, L., Mage, G. & Delmas, V. Reconstruction 3D vectorielle à partir d'IRM foetale pour l'estimation du poids foetal 2008 90ème Congrès de l'Association des Morphologistes, Bordeaux  conference DOI  
BibTeX:
@conference{Ami2008,
  author = {Olivier Ami and Sylvain Ordureau and Jean-Francois Uhl and JM Garcier and L Boyer and G Mage and Vincent Delmas},
  title = {Reconstruction 3D vectorielle à partir d'IRM foetale pour l'estimation du poids foetal},
  booktitle = {90ème Congrès de l'Association des Morphologistes, Bordeaux},
  year = {2008},
  doi = {http://www.lirmm.fr/~subsol/CAMorpho.0608.pdf}
}
Benadjaoud, Y., Greilsamer, T., Walbron, P., Uhl, J.-F., Riquet, M. & Delmas, V. Etude en 3D des cardiopathies congénitales : exemple de la Tétralogie de Fallot 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Benadjaoud2010,
  author = {Yasmine Benadjaoud and T Greilsamer and P Walbron and Jean-François Uhl and M Riquet and Vincent Delmas},
  title = {Etude en 3D des cardiopathies congénitales : exemple de la Tétralogie de Fallot},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Benadjaoud, Y., Houyel, L., Paul, J.-F. & Delmas, V. Modélisation 3D de la tétralogie de Fallot 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Benadjaoud2010a,
  author = {Yasmine Benadjaoud and L Houyel and Jean-Francois Paul and Vincent Delmas},
  title = {Modélisation 3D de la tétralogie de Fallot},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Bendavid, M., Uhl, J.-F., Ami, S.O.O. & Delmas, V. Apport de la fusion 3D dans le diagnostic des tumeurs primitives NE 2008 90ème Congrès de l'Association des Morphologistes, Bordeaux  conference DOI  
BibTeX:
@conference{Bendavid2008,
  author = {M Bendavid and Jean-François Uhl and Sylvain Ordureau Olivier Ami and Vincent Delmas},
  title = {Apport de la fusion 3D dans le diagnostic des tumeurs primitives NE},
  booktitle = {90ème Congrès de l'Association des Morphologistes, Bordeaux},
  year = {2008},
  doi = {http://www.lirmm.fr/~subsol/CAMorpho.0608.pdf}
}
Bonnefond, P., Uhl, J.-F., marini, D., Ordureau, S., Ami, O. & Delmas, V. Les nouveaux outils de dissection virtuelle : Apport dans la diagnostic et le suivi post opératoire des cardiopathies congénitales 2008 90ème Congrès de l'Association des Morphologistes, Bordeaux  conference DOI  
BibTeX:
@conference{Bonnefond2008,
  author = {P Bonnefond and Jean-François Uhl and D marini and Sylvain Ordureau and Olivier Ami and Vincent Delmas},
  title = {Les nouveaux outils de dissection virtuelle : Apport dans la diagnostic et le suivi post opératoire des cardiopathies congénitales},
  booktitle = {90ème Congrès de l'Association des Morphologistes, Bordeaux},
  year = {2008},
  doi = {http://www.lirmm.fr/~subsol/CAMorpho.0608.pdf}
}
Buthiau, D. & Ordureau, S. New imaging in oncology 2007 International Congress of Anti-Cancer Treatment (ICACT)  conference URL 
BibTeX:
@conference{Buthiau2007,
  author = {Didier Buthiau and Sylvain Ordureau and},
  title = {New imaging in oncology},
  booktitle = {International Congress of Anti-Cancer Treatment (ICACT)},
  year = {2007},
  url = {http://www.icact.fr/}
}
Castro, A., Vidal, C., Ordureau, S. & Gombergh, R. Wich is the best measurement of visceral obesity : 2D or 3D scan imaging 2007 Radiological Society of North America, annual meeting (RSNA)  conference URL 
BibTeX:
@conference{Castro2007,
  author = {Alber Castro and Catherine Vidal and Sylvain Ordureau and Rodolphe Gombergh},
  title = {Wich is the best measurement of visceral obesity : 2D or 3D scan imaging},
  booktitle = {Radiological Society of North America, annual meeting (RSNA)},
  year = {2007},
  url = {http://rsna2007.rsna.org/}
}
Ferdinand, A., Uhl, J.-F. & Delmas, V. Modélisation 3D des malformations veineuse congénitales : cas clinique d’une veine marginale persistante 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Ferdinand2010,
  author = {Arthur Ferdinand and Jean-Francois Uhl and Vincent Delmas},
  title = {Modélisation 3D des malformations veineuse congénitales : cas clinique d’une veine marginale persistante},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Goldberg, M., Marchadier, A., Septier, D., Cherifi, H., Vidal, C., Sugars, R., Oldberg, A., Kilts, T. & Young, M. Fibromodulin is implicated in bones and teeth mineralization 2009 International Association of Dental Research (IADR)  conference DOI URL 
Abstract: Small leucine-rich proteoglycans are components of the extracellular matrix of mineralized tissues. DS/CSPGs (i.e. decorin and biglycan) and KSPGs (i.e. lumican, osteoadherin and fibromodulin, or Fmod) have been found in dentin, cementum and bone. However, the role these PGs might have in promoting or inhibiting mineralization is still unclear.

Western blotting revealed that the Fmod MW was higher in bone (52kDa) compared with with dental tissues (52 and 40kDa). Strong immunostaining of Fmod was restricted to i) the distal border of secretory odontolblasts, ii) the distal junctional complex of secretory ameloblasts, iii) the stratum intermedium and there was faint staining in the predentin.

Fmod deficient (KO) tissues have collagen fibrils with a larger diameter than controls (WT). Dentin was also hypomineralized in the Fmod KO. In molars, the pulp chambers were wider in the KO compared to WT, and the observed differences in dentin formation were confirmed by X-ray microcomputed tomography. Structural defects were observed within the forming enamel in the incisor of the KO mice. Compensatory mechanisms appeared to partially hide the defects of dental tissues, most likely by DSP, DMP-1 and BSP which were over-expressed, but not by OPN which showed no differences between the WT and KO tissues.

Using the scanning electron microscopy, backscattering analysis of sections of mandibles of day 21 mice revealed larger surfaces occupied by the bone medulla in the KO. X-ray tomography revealed severe hypomineralization of bone, mostly in the distal part of the mandible of KO mice, including the condyle, coronoïd, angula and the vertical branch, The alveolar bone located in the central part was also defective, whereas changes were more subtle in the anterior (rostral) part. The bone deficiency in the KO was even more severe in 10 weeks- old mice.

Altogether, these data suggest that Fmod is a crucial factor in regulating mineralization. We delineate the differences between the three different parts of the mandibular bone, as well as differences between bone and tooth tissues.

BibTeX:
@conference{Goldberg2009,
  author = {Michel Goldberg and Arnaud Marchadier and Damien Septier and Hafida Cherifi and Catherine Vidal and R Sugars and A Oldberg and T Kilts and Maryan Young},
  title = {Fibromodulin is implicated in bones and teeth mineralization},
  booktitle = {International Association of Dental Research (IADR)},
  year = {2009},
  url = {http://www.iadr.org},
  doi = {http://iadr.confex.com/iadr/ced09/webprogram/Paper123658.html}
}
Goldberg, M., Ono, M., Septier, D., Marchadier, A., Ordureau, S., Vidal, C., Kilts, T., Bi, Y., Embree, M. & Young, M. Importance of fibromodulin on dental tissues and mandibular bone formation 2008 International Association of Dental Research (IADR)  conference URL 
BibTeX:
@conference{Goldberg2008,
  author = {Michel Goldberg and M Ono and Damien Septier and Arnaud Marchadier and Sylvain Ordureau and Catherine Vidal and T Kilts and Y Bi and M Embree and Maryan Young},
  title = {Importance of fibromodulin on dental tissues and mandibular bone formation},
  booktitle = {International Association of Dental Research (IADR)},
  year = {2008},
  url = {http://www.iadr.org}
}
Guilbert, A., Uhl, J.-F., Ordureau, S., Ami, O. & Delmas, V. Les nouveaux outils de dissection virtuelle 2008 90ème Congrès de l'Association des Morphologistes, Bordeaux  conference DOI  
BibTeX:
@conference{Guilbert2008,
  author = {A Guilbert and Jean-Francois Uhl and Sylvain Ordureau and Olivier Ami and Vincent Delmas},
  title = {Les nouveaux outils de dissection virtuelle},
  booktitle = {90ème Congrès de l'Association des Morphologistes, Bordeaux},
  year = {2008},
  doi = {http://www.lirmm.fr/~subsol/CAMorpho.0608.pdf}
}
Lecuyot, G. & Ordureau, S. L'imagerie médicale au service d'une momie 2009
Vol. prépublication n°21, pp. 1-4 
inbook DOI  
Abstract: Une momie découverte au cours des fouilles du musée du Louvre à Saqqara a été
scannée au musée du Caire en 2005. En 2007, la reprise des fichiers par un informaticien spécialisé
dans l’imagerie médicale a permis de réaliser des images virtuelles 3D de la défunte et ainsi
de prolonger l’examen fait en Égypte
BibTeX:
@inbook{Lecuyot2009,
  author = {Guy Lecuyot and Sylvain Ordureau},
  title = {L'imagerie médicale au service d'une momie},
  publisher = {Prépublications de l'Université de Caen Basse-Normandie},
  year = {2009},
  volume = {prépublication n°21},
  pages = {1-4},
  doi = {http://www.unicaen.fr/services/puc/ecrire/preprints/preprint0212009.pdf}
}
Marchadier, A., Catherine Vidal, J.-P.T., Ordureau, S., Lédée, R. & Léger, C. Quantitative CT imaging for adipose tissue analysis in mouse model of obesity 2011 SPIE Medical Imaging,  conference URL 
Abstract: In obese humans CT imaging is a validated method for follow up studies of adipose tissue distribution and quantification of visceral and subcutaneous fat. Equivalent methods in murine models of obesity are still lacking. Current small animal micro-CT involves long-term X-ray exposure precluding longitudinal studies. We have overcome this limitation by using a human medical CT which allows very fast 3D imaging (2 sec) and minimal radiation exposure. This work presents novel methods fitted to in vivo investigations of mice models of obesity, allowing (i) automated detection of adipose tissue in abdominal regions of interest, (ii) quantification of visceral and subcutaneous fat
BibTeX:
@conference{Marchadier2011,
  author = {Arnaud Marchadier and Catherine Vidal, Jean-Pierre Tafani and Sylvain Ordureau and Roger Lédée and Christophe Léger},
  title = {Quantitative CT imaging for adipose tissue analysis in mouse model of obesity},
  booktitle = {SPIE Medical Imaging,},
  year = {2011},
  url = {http://spie.org/app/program/index.cfm?fuseaction=conferencedetail&export_id=x12534&ID=x12171&redir=x12171.xml&conference_id=927825&event_id=894242}
}
Marchadier, A., Vidal, C., Ordureau, S., Lédée, R., Léger, C., Young, M. & Goldberg, M. 3D visualization and quantification of bone and teeth mineralization for the study of osteo/dentinogenesis in mice models 2011 SPIE Medical Imaging  conference URL 
BibTeX:
@conference{Marchadier2011a,
  author = {Arnaud Marchadier and Catherine Vidal and Sylvain Ordureau and Roger Lédée and Christophe Léger and Maryan Young and Michel Goldberg},
  title = {3D visualization and quantification of bone and teeth mineralization for the study of osteo/dentinogenesis in mice models},
  booktitle = {SPIE Medical Imaging},
  year = {2011},
  url = {http://spie.org/app/program/index.cfm?fuseaction=conferencedetail&export_id=x12534&ID=x12171&redir=x12171.xml&conference_id=927829&event_id=894242}
}
Netter, A., Toussaint, P.J., Uhl, J.-F., Leclercq, D., Thiebaut, J.-B., Dronkers, N. & Plaisant, O. Reconstruction 3D du faisceau arqué 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Netter2010,
  author = {Antoine Netter and Paule Joanne Toussaint and Jean-François Uhl and Delphine Leclercq and Jean-Baptiste Thiebaut and Nina Dronkers and Odile Plaisant},
  title = {Reconstruction 3D du faisceau arqué},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Nich, C., Langlois, J., Marchadier, A., Vidal, C., Cohen-Solal, M., Petite, H. & Hamadouche, M. Estrogen Deficiency is Protective Against Particle-Induced Osteolysis 2011 12th EFORT congress, Copenhague, Danemark  conference URL 
BibTeX:
@conference{Nich2011,
  author = {Christophe Nich and Jean Langlois and Arnaud Marchadier and Catherine Vidal and Martine Cohen-Solal and Hervé Petite and Moussa Hamadouche},
  title = {Estrogen Deficiency is Protective Against Particle-Induced Osteolysis},
  booktitle = {12th EFORT congress, Copenhague, Danemark},
  year = {2011},
  url = {http://www.efort.org/}
}
Nich, C., Marchadier, A., Sedel, L., Petite, H. & Hamadouche, M. Decrease in particle-induced osteolysis in ovariectomized mice 2009 Société Internationale de Chirurgie Orthopédique et Traumatologique (SICOT)  conference DOI URL 
Abstract: Post-menopausal osteoporosis is a common disorder that results from increased osteoclastic activity caused by estrogen deficiency.
Whether post-menopausal bone remodeling can alter the response to particulate debris is not known. The purpose of this study was to
evaluate the bone response to polyethylene particles in an estrogen deficient murine model. PE particles were implanted onto the
calvaria of seven wild-type mice and seven ovariectomized (OVX) mice. Calvaria from unimplanted wild-type and OVX mice served as
controls. Calvaria were harvested after 14 days. Skulls were analyzed with a high-resolution micro-CT and by histomorphometry after
staining with Stevenel blue and picrofuschine, and for tartrate-specific alkaline phosphatase. As assessed on micro-CT evaluation,
particles induced significant decrease of bone thickness in wild-type mice (p=0.04), while bone thickness was stable in OVX mice with
particles (p=0.40). The osteoclast number per mm total bone perimeter was in wild-type animals with particles 2.84+/-1.6 and 1.74+/-1.3
in OVX animals with particles (p=0.004). Mean bone loss in wild-type mice was -12+/-10% while mean bone loss was -4.7+/-0.9% in
OVX animals with particles (p=0.004).Particles induced a diminished osteolytic response in OVX mice, suggesting that estrogen
deficiency may have a protective role against particle-induced bone resorption. These important new findings may help to stimulate
clinical studies which may define criteria to better identify patients at risk to develop particle-induced osteolysis.
BibTeX:
@conference{Nich2009,
  author = {Christophe Nich and Arnaud Marchadier and Laurent Sedel and Hervé Petite and Moussa Hamadouche},
  title = {Decrease in particle-induced osteolysis in ovariectomized mice},
  booktitle = {Société Internationale de Chirurgie Orthopédique et Traumatologique (SICOT)},
  year = {2009},
  url = {www.sicot.org},
  doi = {http://www.sicot.org/resources/File/Pattaya/abstract%20cdrom_oral.pdf}
}
Nich, C., Marchadier, A., Sedel, L., Petite, H. & Hamadouche, M. Diminution de l'ostéolyse aux particules d'usure chez des souris ovariectomisées 2009 Société Française de Chirurgie Orthopédique, Paris  conference DOI URL 
BibTeX:
@conference{Nich2009a,
  author = {Christophe Nich and Arnaud Marchadier and Laurent Sedel and Hervé Petite and Moussa Hamadouche},
  title = {Diminution de l'ostéolyse aux particules d'usure chez des souris ovariectomisées},
  booktitle = {Société Française de Chirurgie Orthopédique, Paris},
  year = {2009},
  url = {http://www.sofcot.fr},
  doi = {http://www.sofcot.fr/data/upload/files/PROGRAMME%20SOFCOT%20leg.pdf}
}
Nich, C., Marchadier, A., Sedel, L., Petite, H. & Hamadouche, M. Experimental model of particle-induced periprosthetic osteolysis - micro-scanner evaluation 2009 Société Internationale de Chirurgie Orthopédique et Traumatologique (SICOT)  conference DOI URL 
Abstract: Our objective was to evaluate particle-induced osteolysis both histologically and with the use of a microscanner in a murine model.
Commercially pure polyethylene (PE) particles were implanted onto seven C57BL/J6 mice calvaria after EtO sterilization. Seven mice
were operated without particle implantation (sham group). After one week, animals were sacrificed. Skulls were analyzed with a highresolution
micro-CT to evaluate bone volume (BV) and tissue volume. The undecalcified calvariae were embedded in
methylmehacrylate and sections were obtained. Sections were stained with Stevenel Blue and picrofuschine and a serial section stained
for tartrate-specific acid phosphatase-positive osteoclasts. Mean bone thickness (ratio bone thickness/tissue thickness), sagittal suture
area and osteoclasts number were measured. As assessed on micro-CT, particles induced a significant decrease in bone volume in PEtreated
mice, in comparison with sham animals (p<0.05). Fibrous and granulomatous scar tissue overlying the calvariae was observed
on histological sections. Quantitatively, the mean bone thickness was 60+/-9.5% (range, 42-80%) in PE-treated mice, in comparison
with 48+/-10% (range, 23-73%) (p<0.0001) in sham mice. The sagittal suture area and the osteoclasts number both considerably
increased after particles implantation. MicroCT data significantly correlated with histomorphometry. By implanting PE-particles onto mice
calvaria, we experimentally modeled a bone reaction very similar to the one observed in peri-prosthetic osteolysis. Both microCT and
histological tools allowed us to accurately evaluate particle-induced bone resorption.
BibTeX:
@conference{Nich2009b,
  author = {Christophe Nich and Arnaud Marchadier and Laurent Sedel and Hervé Petite and Moussa Hamadouche},
  title = {Experimental model of particle-induced periprosthetic osteolysis - micro-scanner evaluation},
  booktitle = {Société Internationale de Chirurgie Orthopédique et Traumatologique (SICOT)},
  year = {2009},
  url = {www.sicot.org},
  doi = {http://www.sicot.org/resources/File/Pattaya/abstract%20cdrom_oral.pdf}
}
Nich, C., Marchadier, A., Sedel, L., Petite, H., Vidal, C. & Hamadouche, M. Decrease in particle-induced osteolysis in ovariectomized mice. 2010 J Orthop Res
Vol. 28(2), pp. 178-183 
article DOI URL 
Abstract: Postmenopausal osteoporosis is a common disorder that results from increased osteoclastic activity caused by estrogen deficiency. Whether postmenopausal bone remodeling can alter the response to particulate debris is unknown. The purpose of this study was to evaluate the bone response to polyethylene particles in an ovariectomized murine model. Polyethylene particles were implanted onto the calvaria of seven control mice and seven ovariectomized (OVX) mice, as compared with calvaria from sham-operated and OVX mice. Calvaria were harvested after 14 days. Skulls were analyzed with a high-resolution micro-CT and by histomorphometry after staining with Stevenel blue and picrofuschine, and for tartrate-specific alkaline phosphatase. As assessed by micro-CT, particle implantation induced a significant decrease in bone thickness in control mice, while bone thickness remained stable in OVX mice. In particle-implanted animals, the osteoclast number was 2.84 +/- 0.3 in control mice and 1.74 +/- 0.22 in OVX mice. Mean bone loss was -12% +/- 1.9% in control mice and -4.7% +/- 1.7% in OVX animals. The reduction of osteolytic response suggests that ovariectomy may have a protective role against particle-induced bone resorption.
BibTeX:
@article{Nich2010,
  author = {Christophe Nich and Arnaud Marchadier and Laurent Sedel and Hervé Petite and Catherine Vidal and Moussa Hamadouche},
  title = {Decrease in particle-induced osteolysis in ovariectomized mice.},
  journal = {J Orthop Res},
  year = {2010},
  volume = {28},
  number = {2},
  pages = {178--183},
  url = {http://dx.doi.org/10.1002/jor.20987},
  doi = {http://dx.doi.org/10.1002/jor.20987}
}
Ordureau, S., Kellermann, O., Launay, J.-M. & Vidal, C. 3D scan imaging for exploring genetically modified mice 2007 Radiological Society of North America, annual meeting (RSNA)  conference URL 
BibTeX:
@conference{Ordureau2007,
  author = {Sylvain Ordureau and Odile Kellermann and Jean-Marie Launay and Catherine Vidal},
  title = {3D scan imaging for exploring genetically modified mice},
  booktitle = {Radiological Society of North America, annual meeting (RSNA)},
  year = {2007},
  url = {http://rsna2007.rsna.org/}
}
Ordureau, S. & Lecuyot, G. Apport de l'imagerie médicale 3D à l'étude d'une momie du IVème siècle av. J.C. 2007 Virtual Retrospect, Bordeaux  conference DOI  
Abstract: À la suite d’une série de découvertes faites à partir de 2003 dans le secteur du mastaba d’Akhethetep dans la nécropole de Saqqara en Égypte par la mission du musée du Louvre dirigée par Ch. Ziegler, une des momies les mieux conservées a été scannée au Caire par des collègues égyptiens pour les besoins d’un film destiné à la télévision française (France 3).
La reprise des données par l’équipe Useful Progress traitant d’imagerie médicale a permis d’assembler les différents scanners, de composer une vue complète de la momie, de déshabiller la dépouille de ses linceuls, d’étudier les procédés de momification et de faire l’étude anthropologique du corps de cette jeune femme décédée au IV’ siècle av. J.-C. (travail en cours par Sylvain Ordureau).
BibTeX:
@conference{Ordureau2007a,
  author = {Sylvain Ordureau and Guy Lecuyot},
  title = {Apport de l'imagerie médicale 3D à l'étude d'une momie du IVème siècle av. J.C.},
  booktitle = {Virtual Retrospect, Bordeaux},
  year = {2007},
  doi = {http://www.archeo.ens.fr/IMG/pdf/momie-2.pdf}
}
Ordureau, S., Marchadier, A., Lédée, R., Vidal, C., Tafani, J.-P. & Léger, C. New CT imaging method for adipose tissue analysis in mouse model of obesity 2009 Radiological Society of North America, annual meeting (RSNA)  conference URL 
BibTeX:
@conference{Ordureau2009,
  author = {Sylvain Ordureau and Arnaud Marchadier and Roger Lédée and Catherine Vidal and Jean-Pierre Tafani and Christophe Léger},
  title = {New CT imaging method for adipose tissue analysis in mouse model of obesity},
  booktitle = {Radiological Society of North America, annual meeting (RSNA)},
  year = {2009},
  url = {http://rsna2009.rsna.org/search/search.cfm?action=add&filter=Author&value=63322}
}
Schoell, T. & Delmas, J.-F.U.V. Modélisation 3D des dissections de l’aorte 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Schoell2010,
  author = {Thibault Schoell and Jean-François Uhland Vincent Delmas},
  title = {Modélisation 3D des dissections de l’aorte},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Sirimanna, M., Greilsamer, T., Walbron, P., Uhl, J.-F., Riquet, M. & Delmas, V. Modélisation 3D du conduit thoracique embryonnaire 2010 92ème congrès des Morphologistes, Paris  conference DOI  
BibTeX:
@conference{Sirimanna2010,
  author = {Maheshika Sirimanna and T Greilsamer and P Walbron and Jean-François Uhl and M Riquet and Vincent Delmas},
  title = {Modélisation 3D du conduit thoracique embryonnaire},
  booktitle = {92ème congrès des Morphologistes, Paris},
  year = {2010},
  doi = {http://www.morphologiste.fr/cariboost_files/programme_com_morphologistes_V2.pdf}
}
Uhl, J.-F. Anatomie des veines perforantes fémorales : Apport de l’imagerie par phléboscanner avec reconstruction 3D utilisant les techniques de réalité virtuelle 2008 ANGÉIOLOGIE
Vol. 60, pp. 9-11 
article URL 
BibTeX:
@article{Uhl2008,
  author = {Jean-François Uhl},
  title = {Anatomie des veines perforantes fémorales : Apport de l’imagerie par phléboscanner avec reconstruction 3D utilisant les techniques de réalité virtuelle},
  journal = {ANGÉIOLOGIE},
  year = {2008},
  volume = {60},
  pages = {9-11},
  url = {http://www.angeiologie.fr/wp/?p=661}
}
Uhl, J.-F. & Ordureau, S. New computer tools for virtual dissection to study the anatomy of the vascular system 2008 Phlebolymphology
Vol. 15, pp. 151-155 
article URL 
Abstract: The aim of this paper is to demonstrate the major role played by the new computerized imaging tools available today in the fields of morphology and vascular anatomy. For anatomical studies or educational purposes, they enhance classic techniques.
Three-dimensional reconstruction, which is already used in daily clinical practice, will be the basis for computation of validated volumetric protocols enhancing our diagnostic, prognostic, and therapeutic methods. It is also a fantastic educational tool: interactivity and virtual dissection make it simple, efficient, attractive, and easily understandable, particularly in the field of venous anatomy
BibTeX:
@article{Uhl2008a,
  author = {Jean-François Uhl and Sylvain Ordureau},
  title = {New computer tools for virtual dissection to study the anatomy of the vascular system},
  journal = {Phlebolymphology},
  year = {2008},
  volume = {15},
  pages = {151-155},
  url = {http://www.phlebolymphology.org/2009/04/new-computer-tools-for-virtual-dissection-to-study-the-anatomy-of-the-vascular-system/}
}
Uhl, J.-F., Ordureau, S. & delmas, V. The new tools of virtual dissection to study venous anatomy 2008 World Congress of the International Unioon of Angiology  conference  
BibTeX:
@conference{Uhl2008b,
  author = {Jean-François Uhl and Sylvain Ordureau and Vincent delmas},
  title = {The new tools of virtual dissection to study venous anatomy},
  booktitle = {World Congress of the International Unioon of Angiology},
  year = {2008}
}
Uhl, J.-F., Ordureau, S. & Delmas, V. New virtual dissection tools for the study of venous anatomy 2008 e-mémoires de l'Académie Nationale de Chirurgie
Vol. 7, pp. 39-42 
article URL 
BibTeX:
@article{Uhl2008c,
  author = {Jean-François Uhl and Sylvain Ordureau and Vincent Delmas},
  title = {New virtual dissection tools for the study of venous anatomy},
  journal = {e-mémoires de l'Académie Nationale de Chirurgie},
  year = {2008},
  volume = {7},
  pages = {39-42},
  url = {http://www.bium.univ-paris5.fr/acad-chirurgie/ememoires/005_2008_7_2_039x042.pdf}
}
Sylvain Ordureau et Arnaud Marchadier Biofutur 2011
Vol. 30(317) 
periodical DOI URL 
BibTeX:
@periodical{Lavoisier2011,,
  title = {Biofutur},
  year = {2011},
  volume = {30},
  number = {317},
  url = {http://www.biofutur.com},
  doi = {http://www.usefulprogress.com/Publication/Articles/Biofutur_2011-01.pdf}
}
S. Lacerda-Pinheiro, S. Dimitrova-Nakov, Y. Harichane, M. Souyri, L. Petit-Cocault, L. Legrès, A. Marchadier,5, A. Baudry, S. Ribes, M. Goldberg, O. Kellermann and A. Poliard European Cells and Materials 2012
Vol. 23(371-386) 
periodical DOI URL 
BibTeX:
@article{ECM2012,
  author = {S. Lacerda-Pinheiro, S. Dimitrova-Nakov, Y. Harichane, M. Souyri, L. Petit-Cocault, L. Legrès,
A. Marchadier,5, A. Baudry, S. Ribes, M. Goldberg, O. Kellermann and A. Poliard},
  title = {CONCOMITANT MULTIPOTENT AND UNIPOTENT DENTAL PULP PROGENITORS AND THEIR RESPECTIVE CONTRIBUTION TO MINERALISED TISSUE FORMATION},
  journal = {European Cells and Materials},
  year = {2012},
  volume = {23},
  pages = {371-386},
  url = {http://www.ecmjournal.org}
  doi = {http://www.usefulprogress.com/ppt/lacerda-et-al2012.pdf}
}

Created by JabRef on 11/01/2011.